Chemotherapy NCLEX Questions 1-5

Try answering the following Chemotherapy NCLEX Questions. Good luck.

1. Chemotherapy dosage is frequently based on total body surface area (BSA), so it is important for the nurse to perform which assessment before administering chemotherapy?

a) Measure the client’s abdominal girth.
b) Calculate the client’s body mass index.
c) Ask the client about his or her weight and height.
d) Measure the client’s current weight and height.

2. A client with squamous cell carcinoma of the larynx is receiving bleomycin intravenously. The nurse caring for the client anticipates that which diagnostic study will be prescribed?

a) Echocardiography
b) Electrocardiography
c) Cervical radiography
d) Pulmonary function studies

3. Chemotherapy NCLEX Questions about a client with acute myelocytic leukemia who is being treated with busulfan (Myleran, Busulfex). Which laboratory value would the nurse specifically monitor during treatment with this medication?

a) Clotting time
b) Uric acid level
c) Potassium level
d) Blood glucose level

4. A client with small cell lung cancer is being treated with etoposide (Toposar). The nurse monitors the client during administration, knowing that which adverse effect is specifically associated with this medication?

a) Alopecia
b) Chest pain
c) Pulmonary fibrosis
d) Orthostatic hypotension

5. A clinic nurse prepares a teaching plan for a client receiving an antineoplastic medication. When implementing the plan, the nurse should make which statement to the client?

a) “You can take aspirin (acetylsalicylic acid) as needed for headache.”
b) “You can drink beverages containing alcohol in moderate amounts each evening.”
c) “You need to consult with the health care provider (HCP) before receiving immunizations.”
d) “It is fine to receive a flu vaccine at the local health fair without HCP approval because the flu is so contagious.”





Chemotherapy NCLEX Questions
Answers and Rationale

1) D
- Rationale: To ensure that the client receives optimal doses of chemotherapy, dosing is usually based on the total body surface area (BSA), which requires a current accurate height and weight for BSA calculation (before each medication administration). Asking the client about his or her height and weight may lead to inaccuracies in determining a true BSA and dosage. Calculating body mass index and measuring abdominal girth will not provide the data needed.

- Test-Taking Strategy: Recall the basis for dosing chemotherapy. Recalling that a current accurate height and weight need to be obtained for BSA calculation and chemotherapy dosing will direct you to the correct option. Eliminate option C because it is an unreliable way of obtaining the information. Next, eliminate options A and B because they are comparable or alike and do not relate to chemotherapy dosing.

2) D
- Chemotherapy NCLEX Questions Rationale: Bleomycin is an antineoplastic medication that can cause interstitial pneumonitis, which can progress to pulmonary fibrosis. Pulmonary function studies along with hematological, hepatic, and renal function tests need to be monitored. The nurse needs to monitor lung sounds for dyspnea and crackles, which indicate pulmonary toxicity. The medication needs to be discontinued immediately if pulmonary toxicity occurs. Options A, B, and C are unrelated to the specific use of this medication.

- Test-Taking Strategy: Eliminate options A and B first because they are cardiac-related and are therefore comparable or alike. From the remaining options, use the ABCs— airway, breathing, and circulation— to direct you to the correct option.

3) B
- Rationale: Busulfan (Myleran, Busulfex) can cause an increase in the uric acid level. Hyperuricemia can produce uric acid nephropathy, renal stones, and acute kidney injury. Options A, C, and D are not specifically related to this medication.

- Test-Taking Strategy: Focus on the subject, a specific laboratory value. It is necessary to know the adverse effects associated with this medication. Recalling that busulfan increases the uric acid level will direct you to the correct option.

4) D
- Rationale: An adverse effect specific to etoposide is orthostatic hypotension. Etoposide should be administered slowly over 30 to 60 minutes to avoid hypotension. The client’s blood pressure is monitored during the infusion. Hair loss occurs with nearly all the antineoplastic medications. Chest pain and pulmonary fibrosis are unrelated to this medication.

- Chemotherapy NCLEX Questions Test-Taking Strategy: Eliminate option A first because this adverse effect is associated with many of the antineoplastic agents. Eliminate options B and C next because they are comparable or alike and are unrelated to etoposide. Note that the question asks for the adverse effect specific to this medication. Correlate hypotension with etoposide.

5) C
- Rationale: Because antineoplastic medications lower the resistance of the body, clients must be informed not to receive immunizations without an HCP’s approval. Clients also need to avoid contact with individuals who have recently received a live virus vaccine. Clients need to avoid aspirin and aspirin-containing products to minimize the risk of bleeding, and they need to avoid alcohol to minimize the risk of toxicity and side/ adverse effects.

- Test-Taking Strategy: Focus on the subject, client teaching about an antineoplastic medication, and think about the side/ adverse effects of antineoplastic medications. Recalling that antineoplastic medications lower the resistance of the body will direct you to the correct option.


After you reviewed your answers through its rationale, you can now proceed to the next set of questions:

Chemotherapy NCLEX Questions 6-10